PFI4是一种可渗透细胞的选择性BRPF1溴结构域抑制剂，IC50为 80 nM，作用于BRPF1比作用于其他溴结构域选择性强 100 多倍。

PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.

PFI-4 is cell permeable, and acts by displacing the BRPF1 bromodomain from Histone H3.3. [1]

900305-37-5

C21H24N4O3

380.448

PFI4

DMSO:14 mg/mL (36.8 mM)
Ethanol:5 mg/mL (13.14 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years