PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.

PROTAC BET Degrader-1 is a potent BET degrader based on PROTAC, decreases the level of BRD2, BRD3, and BRD4 proteins in RS4;11 cells at 3-10 nM, and inhibits the growth of this cell line (IC50 of 4.3 nM and 45.5 nM for MOLM-13 cells)[1].

2093386-22-0

C44H45N11O9

871.9

DMSO:50 mg/mL (57.35 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years