SW155246 是选择性 DNA 甲基转移酶 (DNMT1) 抑制剂，能够抑制 hDNMT1 (IC50:1.2 μM) 以及mDNMT3A (IC50:38 μM)。它能够促使A549细胞中肿瘤抑制基因RasSF1的重新表达，可用于研究癌症和其他疾病。

SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.

420092-79-1

C16H11ClN2O5S

378.78

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years