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FASN-IN-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FASN-IN-3图片
CAS NO:2097262-60-5
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
FASN-IN-3 是脂肪酸合酶抑制剂,摘自专利文献 US20170119786A1 中的化合物 242A。

产品描述

FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).

体外活性

For monocytes, FASN-IN-3 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation.Human PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist.?Stimulation with either LPS or LTA plus DMSO, the solvent for FASN-IN-3 , results in secretion of IL-1 beta.?FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation.

Cas No.

2097262-60-5

分子式

C24H24N4O

分子量

384.47

储存和溶解度

DMSO:33.33 mg/mL (86.69 mM),ultrasonic and warming and heat to 80°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years