您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > BI 99179
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
BI 99179
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BI 99179图片
CAS NO:1291779-76-4
包装与价格:
包装价格(元)
50 mg电议
100 mg电议

产品名称
BI99179
产品介绍

产品描述

BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1].

体外活性

BI 99179 is potent in the mouse hypothalamic N-42 cell with an IC50 of 0.6 μM and it shows no significant LDH release in the cytotoxicity assay up to 30 μM[1].

体内活性

BI 99179 has a super pharmacokinetic profile in male Han/Wistar rats (oral application of 4 mg/kg)with half life (t1/2) of 3.0 h[1].

Cas No.

1291779-76-4

分子式

C23H25N3O3

分子量

391.46

别名

BI99179

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years