4-Aminoantipyrine是一种检测试剂，在过氧化物酶与苯酚存在时，用于葡萄糖测定。

4-Aminoantipyrine is a reagent for glucose determination in the presence of peroxidase and phenol.

The level of glutathione(GSH) in single erythrocytes is impacted slightly at low AAP(4-aminoantipyrine) concentrations probably due to the protection of glutathione reductase. When AAP concentration further increases, AAP has a significant influence on GSH[2].

4-aminoantipyrine (4-AA) is not genotoxic and mutagenic in vivo, it can interfere with DNA damaging agents biological activities and may reduce the effectiveness of DNA damage-based chemotherapy[3].

Erythrocytes in PBS are incubated for 2 h at ambient temperature (without mixing) with AAP in concentrations from 1 × 10−6 mol/L to 1 × 10−3 mol/L. Sample of erythrocytes without AAP is used as control. After the exposure of AAP, erythrocytes are washed with borate buffer (pH 9.0) 2 times by centrifuging and determined for GSH. (Only for Reference)

83-07-8

C11H13N3O

203.245

Minoazophene;Solnapyrin-A;NSC 60242;Aminoantipyrin;4-氨基安替比林;4-Aminoantipyrine

H2O:37 mg/mL(182.1 mM)
Ethanol:40 mg/mL (196.81 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years