TMS 是一种白藜芦醇的甲基化衍生物，也是具有选择性的CYP1B1竞争性抑制剂，其IC50=6 nM，Ki=3 nM。它对 CYP1A1 (IC50:300 nM) 及 CYP1A2 (IC50:3.1 μM) 的抑制作用较小。它具有抗癌作用。

TMS is a very selective and potent competitive inhibitor of P450 1B1 (CYP1A1).

Twenty-four hours after incubation with the 10 μM DOX in the presence and absence of 0.5 μM TMS, approximately 1.5 × 106 cells per six-well culture plate were collected in 100 μl lysis buffer (50 mM HEPES, 0.5 M sodium chloride, 1.5 mM magnesium chloride, 1 mM EDTA, 10% glycerol (v/v), 1% Triton X-100, and 5 μl/ml of protease inhibitor cocktail).

Mice were administered 300 μg/kg of selective inhibitor of P450 1B1, TMS or its vehicle (dimethyl sulfoxide), i.p. every third day for the duration of the experimental period

24144-92-1

C18H20O4

300.354

(E)-2,3',4,5'-tetramethoxystilbene;2,3',4,5'-Tetramethoxystilbene

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years