Talarozole 是一种口服性全反式维甲酸代谢阻断剂，可抑制 CYP26A1 和 CYP26B1，IC50 分别为 5.4 和 0.46 nM。它用于治疗痤疮、牛皮癣和其他角化疾病。

Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of acne, psoriasis and other keratinization disorders.

201410-53-9

C21H23N5S

377.51

R115866;他拉罗唑

DMSO:36 mg/mL (95.36 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years