Lp-PLA2-IN-1 是脂蛋白相关磷脂酶 A2 (Lp-PLA2) 抑制剂。它有潜力用于动脉粥样硬化、阿尔茨海默氏病的研究。

Lp-PLA2 -IN-1 suppresses Lp-PLA2 activity processes for their preparation. Lp-PLA2 -IN-1also inhibits to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example, atherosclerosis, Alzheimer's disease.

Lp-PLA2 is a phospholipase A2 enzyme involved in the hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2 travels with LDL and rapidly cleaves oxidized phosphatidylcholine molecules derived from the oxidation of LDL[1].

1420367-28-7

C21H17F5N4O3

468.38

Lp-PLA2 inhibitor 1;Lp-PLA2 -IN-1

Ethanol:20 mg/mL (42.7 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years