您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > (Rac)-BMS-816336
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
(Rac)-BMS-816336
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(Rac)-BMS-816336图片
包装与价格:
包装价格(元)
50 mg电议
100 mg电议

产品介绍
(Rac)-BMS-816336 (Compound 6n) 是 BMS-816336 的外消旋体。(Rac)-BMS-816336 是人和小鼠 11β-羟类固醇脱氢酶 1 型 (11β-HSD1) 的有效抑制剂,其IC50分别为 10 nM 和 68 nM,并具有良好的代谢稳定性 。

产品描述

(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme inhibitor with IC 50 s of 10 nM and 68 nM, respectively. (Rac)-BMS-816336 has good metabolic stability [1].

体内活性

(Rac)-BMS-816336 (compound 6n) has good metabolic stability with the remaining rates in human, mouse and rats of 88%,82% and 72%, respectively [1].

Cas No.

T12663

分子式

C21H27NO3

分子量

341.44

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years