Pranidipine 是一种高效且长效的 1,4-二氢吡啶钙通道阻滞剂,可延长乙酰胆碱诱导的内皮松弛以及硝酸甘油诱导的内皮松弛,具有抗高血压作用。
产品描述
Pranidipine is a novel, long-acting 1,4-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence of endothelium. It also has antihypertensive activity.
体内活性
Pranidipine enhances cyclic GMP-dependent nitric oxide-induced relaxation of rat aorta.
Cas No.
99522-79-9
分子式
C25H24N2O6
分子量
448.47
别名
普拉地平;OPC-13340
储存和溶解度
DMSO:270 mg/mL (602.05 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years