Mirogabalin 是一种高效的、选择性的 α2δ-1 配体,作用于电压敏感性钙通道复合体的α2δ-1亚基。
产品描述
Mirogabalin is a calcium channel blocker with analgesic effects.
体内活性
Mirogabalin has potent and sustained analgesic effects (ED50 = 2.5 mg/kg) in rats with diabetes induced by streptozotocin .?Mirogabalin does not inhibit activities associated with CNS adverse effects of analgesics, such as rotarod performance (ID50 = 9.4 mg/kg) or locomotor activity (ID50 = 43.9 mg/kg), at its effective dose.
Cas No.
1138245-13-2
分子式
C12H19NO2
分子量
209.289
别名
DS5565
储存和溶解度
DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years