Etripamil 是一种短效L型钙通道拮抗剂,可用于治疗阵发性室上性心动过速的研究。它通过抑制房室结细胞中钙慢通道的钙离子流入,显示房室结传导并延长房室结不应期
产品描述
Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel. It has a rapid onset of action designed for intranasal administration. It is also used to treat Paroxysmal Supraventricular Tachycardia.
体外活性
Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells.
Cas No.
1593673-23-4
分子式
C27H36N2O4
分子量
452.59
别名
MSP-2017;(-)-MSP-2017
储存和溶解度
Ethanol:110 mg/mL (243.05 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years