Berubicin HCl (RTA-774; WP-769), an anthracycline derivative, is a novel and potent DNA intercalator and antineoplastic agent. Acting by intercalating into DNA and interrupting the activity of topoisomerase II, leading to the inhibition of DNA replication and repair, and RNA and protein synthesis. Unlike other anthracycline derivatives, Berubicin is able to cross the blood-brain barrier (BBB).
纯度:≥98%
CAS:293736-67-1