Pumaprazole 是一种有效的、可逆的质子泵拮抗剂。

Pumaprazole is an antagonist of a reversible proton pump.

Pumaprazole shows identical ID50 values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23), and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compared to ranitidine. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect[1].

158364-59-1

C19H22N4O2

338.4

BY-841;普马拉唑

DMSO:55 mg/ml (162.53 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years