ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.

ERK1/2 inhibitor 1 ?shows excellent antiproliferative potency with IC50s of 7.5 and 4.9 nM in ?Colo205 cells and A375, respectively.

2095719-90-5

C29H32ClN5O4

550.05

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years