LUT014 是B-Raf抑制剂,IC50值为 11.7 nM,用于减少与 EGFR 抑制剂相关限制剂量的痤疮样病变研究。详细信息请参考专利文献 WO 2019026065A2。
产品描述
LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.
Cas No.
2274819-46-2
分子式
C27H19F3N8O
分子量
528.49
储存和溶解度
DMSO:50 mg/mL (94.61 mM),Need ultrasonic
H2O:< 0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years