DilmaPimod 是一种 p38 MAPK 的强效抑制剂,可抑制慢性阻塞性肺疾病的炎症。
产品描述
Dilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
体外活性
p38 MAPK signaling potently inhibited by Dilmapimod, measured by inhibition of sorbitol-induced pHSP27 expression.
Cas No.
444606-18-2
分子式
C23H19F3N4O3
分子量
456.42
别名
度马莫得;GW 681323;SB-681323
储存和溶解度
DMSO:125 mg/mL (273.87 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years