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Proparacaine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Proparacaine hydrochloride图片
CAS NO:5875-06-9
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Proparacaine HCl
Proxymetacaine Hydrochloride
盐酸丙美卡因
产品介绍
Proparacaine hydrochloride 是 LIDOcaine的衍生物,具有糖皮质激素样活性和免疫调节作用。

产品描述

Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.

体外活性

Proparacaine is more potent and less toxic than cocaine. [1] Proparacaine significantly increases in FHV-1 (P< 0.01), C. felis, and 28S rDNA Ct values when fusidic acid is used. [2]

体内活性

Proparacaine inhibits corneal epithelial migration and adhesion through alteration of the actin cytoskeleton. [3] Proparacaine acts like bupivacaine or lidocaine and produces dose-related spinal blockades of motor function, proprioception and nociception. Intrathecal proxymetacaine also produces longer sensory blockade than motor blockade. [4]

Cas No.

5875-06-9

分子式

C16H26N2O3·HCl

分子量

330.86

别名

Proparacaine HCl;Proxymetacaine Hydrochloride;盐酸丙美卡因

储存和溶解度

H2O:61 mg/mL (184.4 mM)
DMSO:10 mg/mL (30.2 mM)
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years