KIF18A-IN-2 是有丝分裂驱动蛋白 Kif18A 的抑制剂，IC50 为 28 nM，可用于染色体不稳定性相关漏洞的研究。

KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.

In Female athymic nude mice injected with human OVCAR-3 HGSOC cells, KIF18A-IN-2 (100 mg/kg; i.p.) exhibits a significant and sustained pharmacodynamic response and increases the number of mitotic cells (pH3 positive cells) in tumor tissues[1].

2600559-20-2

C25H34N4O5S2

534.69

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years