Crolibulin 是一种微管蛋白聚合抑制剂，具有诱导凋亡和抑制细胞生长的作用。它有抗肿瘤活性，还具有心血管毒性和神经毒性。

Crolibulin is an inhibitor of small molecule tubulin polymerization.

Crolibulin shows significant cytotoxic activity against HT-29 cells, with an IC50 of 0.52 μM[2]. Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage[2].

1000852-17-4

C18H17BrN4O3

417.26

EPC2407

DMSO:120 mg/mL (287.59 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years