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CK-869
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CK-869图片
CAS NO:388592-44-7
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
CK-869 是一种肌动蛋白相关蛋白 2/3 复合体抑制剂,其IC50值为 7 μM。

产品描述

CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.

体外活性

CK-869 inhibits comet tail formation by L. monocytogenes with an IC50 value of 7 μM.It also impairs cell adhesion and cell spreading in MCF10A human breast epithelial cells[1].

细胞实验

Cells were treated in suspension with different concentrations of the compounds, allowed to adhere to the surface of a tissue culture dish for one hour, washed and the number of adherent cells counted and presented as a fraction of untreated cells (10X lens, 10 fields/condition).?For cell spreading assays, cells were treated with CK-869 in suspension, plated on coverslips coated with 5 μg/ml fibronectin for imaging[1].

Cas No.

388592-44-7

分子式

C17H16BrNO3S

分子量

394.28

储存和溶解度

DMSO:75 mg/mL (190.22 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years