TASP0415914 是一种具有口服活性的PI3Kγ抑制剂,其 IC50=29 nM。它是一种Akt抑制剂,其 IC50=294 nM。它可用于研究炎症性疾病。
产品描述
TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T
体内活性
TASP0415914 demonstrated good potency in a cell-based assay and, furthermore, exhibited in vivo efficacy in a collagen induced arthritis (CIA) model in mice after oral administration[1].
Cas No.
1292300-75-4
分子式
C13H17N5O3S
分子量
323.37
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years