Islatravir 是一种核苷逆转录酶抑制剂，是抗HIV-1药物，对 HIV-1 (WT)，HIV-1 (M184V)，HIV-1 (MDR) 的EC50值分别为 0.068 nM，3.1 nM 和 0.15 nM。

Islatravir is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively).

865363-93-5

C12H12FN5O3

293.25

MK-8591

H2O:3 mg/mL (10.23 mM),ultrasonic and warming and heat to 60°C
DMSO:100 mg/mL (341.01 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years