Amorolfine HCL 是一种抗真菌试剂。它通过选择性地中断麦角甾醇合成途径中的两个步骤并最终破坏真菌细胞膜的功能和结构来发挥抗真菌活性。阿莫罗芬是一种吗啉类抗真菌药物，可抑制 D14 还原酶和 D7-D8 异构酶。这些酶可以消耗麦角甾醇并导致木甾醇在真菌细胞质细胞膜中积累。

Amorolfine HCL is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase. These enzymes can deplete ergosterol and cause ignosterol to accumulate in the fungal cytoplasmic cell membranes.

106614-68-0

C21H36ClNO

353.98

DMSO:12.5 mg/mL (35.31 mM),Need ultrasonic
H2O:3.33 mg/mL (9.41 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years