您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Bemnifosbuvir hemisulfate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Bemnifosbuvir hemisulfate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bemnifosbuvir hemisulfate图片
CAS NO:2241337-84-6
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
AT-527
产品介绍
Bemnifosbuvir hemisulfate 是一种 HCV 病毒复制抑制剂。

产品描述

Bemnifosbuvir hemisulfate is a potent inhibitor of HCV virus replication.

体外活性

The potent in vitro activity of AT-511, the free base of bemnifosbuvir hemisulfate, against several coronaviruses, including SARS-CoV-2. In normal human airway epithelial cells, the concentration of AT-511 required to inhibit replication of SARS-CoV-2 by 90% (EC90) was 0.47?μM, very similar to its EC90 against human coronavirus (HCoV)-229E, HCoV-OC43, and SARS-CoV in Huh-7 cells[1].

体内活性

When given orally to rats and monkeys, bemnifosbuvir hemisulfate preferentially delivered high levels of AT-9010 in the liver in vivo.These favorable preclinical attributes support bemnifosbuvir hemisulfate may increase SVR rates[2].

Cas No.

2241337-84-6

分子式

C48H68F2N14O18P2S

分子量

1261.16

别名

AT-527

储存和溶解度

DMSO:170 mg/mL (269.60mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years