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Merafloxacin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Merafloxacin图片
CAS NO:91188-00-0
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
CI 934
产品介绍
MeRafloxacin是一种氟喹诺酮类抗菌药物,也被确定为 SARS-CoV-2 的 1 PRF 抑制剂。它对革兰氏阳性菌和革兰氏阴性菌具有体外活性。

产品描述

Merafloxacin is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.

体外活性

Frameshift inhibition by merafloxacin is robust to mutations within the pseudoknot region and is similarly effective on -1 PRF of other beta coronaviruses.?Importantly, frameshift inhibition by merafloxacin substantially impedes SARS-CoV-2 replication in Vero E6 cells, thereby providing the proof of principle of targeting -1 PRF as an effective antiviral strategy for SARS-CoV-2.

Cas No.

91188-00-0

分子式

C19H23F2N3O3

分子量

379.408

别名

CI 934

储存和溶解度

H2O:Insoluble
DMSO:3.79 mg/ml (10 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years