EIDD-2801 是核糖核苷类似物 N 4-羟基胞苷 (EIDD-1931) 的异丙酯前药，已显示出广泛的流感病毒和多种冠状病毒活性。

EIDD-2801 is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multiple coronaviruses activity.

EIDD-2801 was orally bioavailable in ferrets and nonhuman primates.?Therapeutic oral dosing of influenza virus-infected ferrets reduced group pandemic 1 and group 2 seasonal influenza A shed virus load by multiple orders of magnitude and alleviated fever, airway epithelium histopathology, and inflammation, whereas postexposure prophylactic dosing was sterilizing[1].

2349386-89-4

C13H19N3O7

329.309

Molnupiravir

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years