GRL-0496 是氯吡啶酯衍生物，是有效的SARS-CoV 3CLpro抑制剂，IC50为 30 nM。GRL-0496显示出抗SARS-CoV病毒活性，EC50为 6.9 μM。

GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μM.

1087243-14-8

DMSO:100 mg/mL (366.72 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years