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S119-8
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
S119-8图片
CAS NO:443639-96-1
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
S119-8 是一种广谱甲型和乙型流感病毒抑制剂,抑制多种乙型流感病毒和耐奥司他韦的甲型流感病毒。

产品描述

RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation. RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.

体外活性

RN-18, that antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G.?RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation.?RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.

Cas No.

443639-96-1

分子式

C23H24N2O

分子量

344.45

储存和溶解度

DMSO:95 mg/mL (249.72 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years