Surfactin 是一种有效的环状脂肽生物表面活性剂,可介导单价和二价阳离子(如钙)穿过脂质双层膜的通量,具有抗菌、抗真菌、抗支原体和溶血作用。
产品描述
Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects.
体外活性
Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes.?surfactin can increase the activity of amoxicillin against avian pathogenic Escherichia coli (APEC) in vitro with antimicrobial assays such as minimum inhibitory concentrations (MIC) and fractional inhibitory concentration (FIC).
体内活性
in the model of chick infection, surfactin exerted adjuvant effects with amoxicillin against APEC by lowering the numerical value of mortality and liver bacterial loads, and regulating the expression of inflammatory cytokines et al.?We concluded that surfactin can act as a novel antimicrobial adjuvant with amoxicillin against AEPC infection in chicken.
Cas No.
24730-31-2
分子式
C53H93N7O13
分子量
1036.34
储存和溶解度
H2O:28.25 mg/mL (27.26 mM),Need ultrasonic
DMSO:47 mg/mL (45.35 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years