Vagistat是一种广谱性的抗真菌咪唑衍生物。它抑制几种皮肤真菌和几种酵母菌的 MIC50分别小于 3.12 mg/L 和 9 mg/L。

Tioconazole is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements.

65899-73-2

C16H13Cl3N2OS

387.7

噻康唑;Vagistat;UK-20349

DMSO:72 mg/mL (185.7 mM)
H2O:<1 mgml
Ethanol:72 mg/mL (185.7 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years