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4-Phenoxybenzylamine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-Phenoxybenzylamine图片
CAS NO:107622-80-0
包装:100 mg
市场价:485元

产品介绍
4-Phenoxybenzylamine 通过稳定无活性构象来抑制NS3蛋白的功能,对 HCV NS3/4a 的 IC50 约为 500 μM。

产品描述

4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .

体外活性

A highly conserved novel binding site located at the interface between the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein is identified. 4-Phenoxybenzylamine binding at this allosteric site inhibits the function of the NS3 protein by stabilizing an inactive conformation therefore it represents a new class of direct-acting antiviral agents.

Cas No.

107622-80-0

分子式

C13H13NO

分子量

199.253

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years