DPN 是一种非甾体雌激素受体ERβ选择性配体，其EC50值为 0.85 nM。DPN 在许多神经系统疾病具有神经保护作用。

DPN is an selective agonist of estrogen receptor β (ERβ) .

DPN exhibits a 70-fold higher relative binding affinity for ERβ (18%) versus ERα (0.25%), about 80-fold higher transcriptional potency (EC50 = 0.85 nM versus 66 nM), and 170-fold higher relative potency (4.6% versus 0.025%) in transcription assays[1]

1428-67-7

C15H13NO2

239.27

Diarylpropionitrile;2,3-双(4-羟苯基)丙腈

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years