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Butoconazole nitrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Butoconazole nitrate图片
CAS NO:64872-77-1
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
RS 35887
硝酸布康唑
产品介绍
Butoconazole nitrate 是一种咪唑类抗真菌药物,可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。

产品描述

Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butoconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms.

体内活性

Dexpanthenol has positive effects on protection of cerebral tissue after ischaemia reperfusion[1]. Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Upregulation of IL-6, IL-1, CYP1B1, CXCL1, CCL18 and KAP 4-2 gene expression and downregulation of psorasin mRNA and protein expression are identified in samples treated topically with dexpanthenol[2].

Cas No.

64872-77-1

分子式

C19H18Cl3N3O3S

分子量

474.78

别名

RS 35887;硝酸布康唑

储存和溶解度

H2O:<1 mgml
DMSO:88 mg/mL (185.3 mM)
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years