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OP-1074
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
OP-1074图片
CAS NO:1443752-76-8
包装与价格:
包装价格(元)
5 mg电议
10 mg电议

产品介绍

产品描述

OP-1074 is a pure antiestrogen and a selective degrader of ER, shows specific antiestrogenic activity for ERα and ERβ.

体外活性

OP-1074 as a pure antiestrogen and a selective ER degrader (PA-SERD) that is efficacious in shrinking tumors in a tamoxifen-resistant xenograft model. Biochemical and crystal structure analyses reveal a structure activity relationship implicating the importance of a stereospecific methyl on the pyrrolidine side chain of OP-1074, particularly on helix 12.

Cas No.

1443752-76-8

分子式

C29H31NO4

分子量

457.56

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years