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SK33
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SK33图片
CAS NO:1928724-23-5
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议

产品介绍
SK33 是一种有效的组织选择性抗雄激素药物,是一种肌醇类似物,能够降低雄激素受体 (AR) 的转录活性。

产品描述

SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.

体外活性

SK33 has a significantly potent activity (IC50:0.2 μM) in LNCaPAR+?cells. SK33 decreases cells enter S-phase in LNCaP cells. In LNCaP/BicR cells, increasing concentrations of SK33 for 96 hours results in a dose-dependent response and an inhibition of cell growth(IC50?: 5 μM for SK33).

体内活性

AR transcriptional activity inhibited by SK33 after 50 mg/kg treatment for 24 hours.

Cas No.

1928724-23-5

分子式

C20H13F9N2O3

分子量

500.31

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years