Clobetasone butyrate 是糖皮质类固醇,特别是在皮肤上,具有局部抗炎活性。它可用于改善皮质类固醇反应性症状,如特应性皮炎、牛皮癣。
产品描述
Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis. Clobetasone butyrate is a synthetic glucocorticoid. It has topical anti-inflammatory activity especially in skin .
体内活性
Clobetasone butyrate (application on the skin; 0.05%; 7 weeks) causes epidermal thinning in skin. Clobetasone butyrate causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%). Both of which causes severe atrophy[1].
Cas No.
25122-57-0
分子式
C26H32ClFO5
分子量
478.98
储存和溶解度
DMSO:240 mg/mL (501.06 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years