Loteprednol etabonate是具有抗炎活性的皮质类固醇，用于眼科。

Loteprednol Etabonate is an ophthalmic analog of the corticosteroid prednisolone with anti-inflammatory activity.

Loteprednol possesses a metabolically labile function, the 17beta-ester, that is designed to be rapidly deactivated in the systemic circulation. Loteprednol etabonate exhibits a binding affinity which is 4.3 times that of dexamethasone, both compounds having a Hill factor close to 1 whereas PJ90 and PJ91 does not show any affinity to the receptor. [1]

82034-46-6

C24H31ClO7

466.96

氯替泼诺;Alrex;Lotemax

H2O:<1 mgml
DMSO:86 mg/mL (184.2 mM)
Ethanol:4 mg/mL (8.56 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years