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Fludrocortisone acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fludrocortisone acetate图片
CAS NO:514-36-3
包装与价格:
包装价格(元)
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
醋酸氟氢可的松
9α-Fluorcortisol acetate
9α-fluorocortisol acetate
9α-Fludrocortisone acetate
产品介绍
Fludrocortisone acetate 是一种合成的盐皮质激素,可减少尿液中钠丢失量,也用于增加血压,有用于阿狄森氏病的研究潜力。

产品描述

Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2 (PLA2). Fludrocortisone Acetate is the acetate salt of a synthetic fluorinated corticosteroid with anti-inflammatory and antiallergic activities. Inhibition of PLA2 activity prevents the release of arachidonic acid, a precursor of eicosanoids such as prostaglandins and leukotrienes; eicosanoids are important mediators in the pro-inflammatory response mechanism. As a mineralocorticoid-receptor agonist, this agent stimulates Na+ reabsorption and water retention and K+ and H+ secretion in the distal tubules and collecting ducts of the kidney.

Cas No.

514-36-3

分子式

C23H31FO6

分子量

422.493

别名

醋酸氟氢可的松;9α-Fluorcortisol acetate;9α-fluorocortisol acetate;9α-Fludrocortisone acetate

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years