2-Ketoglutaric acid 是 Krebs 循环的中间体，可以产生ATP 或 GTP 。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。

2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.

328-50-7

C5H6O5

146.1

α-酮戊二酸;alpha-酮戊二酸

H2O:50 mg/mL (342.23 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years