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R916562
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
R916562图片
CAS NO:1037798-41-6
包装:5 mg
市场价:9850元

产品介绍

产品描述

R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis.

体内活性

R916562 treatment at 85 mg/kg or 125 mg/kg (orally b.i. d for 21 days) results in statistically significant tumor growth inhibitions of 69% or 83% respectively. R916562 shows 73% reduction in fibroblast growth factor-induced neovascularization in a mouse corneal micropocket assay at a dose of 100 mg/kg and 50% reduction at 50 mg/kg[1].

Cas No.

1037798-41-6

分子式

C26H30ClN9S

分子量

536.1

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years