PKI 14-22 amide, myristoylated Acetate 抑制 cAMP 依赖性蛋白激酶 (PKA) 并阻断脊髓给药 8-溴-cAMP 产生的痛觉过敏。

PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP.

?Myristoylated PKI 14-22 amide reduced the IgG-mediated phagocytic response in a manner of dose-dependent.?When the concentration is higher than 10 μM, PKI 14-22 amide can inhibit neutrophil adhesion, which make the phagocytosis measurements impossible to perform

T21983L

C55H104N20O14

1269.54

PKI 14-22 amide, myristoylated Acetate(201422-03-9 Free base)

DMSO:55 mg/ml (43.32 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years