Insulin cattle 是一种在胰腺 β 细胞中产生的两链多肽激素,在很多哺乳动物细胞培养体系中用作生长因子。
产品描述
Insulin cattle (Insulin from bovine pancreas) is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells。It has often been used as growth supplement in culturing cells.
体外活性
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. And the α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 μg/mL of medium generally.
Cas No.
11070-73-8
分子式
C254H377N65O75S6
分子量
5733.49
别名
Insulin from bovine pancreas;牛胰岛素;胰岛素
储存和溶解度
H2O:11 mg/mL (1.92 mM),ultrasonic and adjust pH to 2 with HCl
Powder: -20°C for 3 years
In solvent: -80°C for 2 years