3MB-PP1 是 Polo 样激酶 1 (PLK1) 的抑制剂,抑制 Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK),IC50 为 2 μM。 3MB-PP1 可用于研究白色念珠菌的细胞分裂和菌丝形成。
产品描述
3MB-PP1 is an inhibitor of Polo-like kinase 1 (PLK1) and inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK) with an IC50 of 2 μM. 3MB-PP1 can be used in studies about cell division and hypha formation of Candida albicans.
体外活性
In a strain bearing analog-sensitive alleles of SSN3(Cdk8), 3MB-PP1 (5 μM) stimulates hyphal growth[1].
Cas No.
956025-83-5
分子式
C17H21N5
分子量
295.38
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years