BML-259 是 CDK5 和 CDK2 的抑制剂，IC50 分别为 64 和 98 nM。 BML-259 可用于癌症和神经退行性疾病治疗的研究。

BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.

BML-259 prevents a large population of cells from NAC-evoked cell death[1].

267654-00-2

C14H16N2OS

260.36

DMF:30 mg/mL
DMSO:PBS (pH 7.2)(1:2):0.3 mg/mL
DMSO:120 mg/mL (460.92 mM),Need ultrasonic
Ethanol:0.25 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years