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Ioversol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ioversol图片
CAS NO:87771-40-2
包装与价格:
包装价格(元)
10 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
MP-328
碘佛醇
产品介绍
Ioversol 是一种非离子碘化造影剂 (CM),不损伤动物的血脑屏障 (BBB),可用于动物实验的 CT 扫描或 x-ray。

产品描述

Ioversol is a nonionic iodinated contrast agent.

体外活性

Ioversol significantly increases apoptosis and caspase-3 protein expression in the NRK-52E cells exposed to ioversol for 4 h. Ioversol treatment induces a significant increase in [Ca2+]i and intracellular ROS.Ioversol (100 mg iodine/ml) exposure induces significantly increased lactate dehydrogenase release and decreased 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl tetrazolium bromide conversion in NRK-52E cells.

体内活性

In comparison with iothalamate, ioversol has a greatly reduced propensity to stimulate the release of endothelin, from cultured cells and when injected into anesthetized rats. Ioversol produces less renal vasoconstriction than does iothalamate, in control and in USIC rats, and the development of radiocontrast nephropathy, assessed by creatinine clearance and morphologic damage to the renal medulla, is largely avoided.

Cas No.

87771-40-2

分子式

C18H24I3N3O9

分子量

807.11

别名

MP-328;碘佛醇

储存和溶解度

DMSO:100 mg/mL (123.90 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years