(+)-Biotin-ONP 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
(+)-Biotin-ONP is an alkyl chain-based PROTAC linker. (+)-Biotin-ONP can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
33755-53-2
分子式
C16H19N3O5S
分子量
365.4
别名
(+)-生物素对硝基苯酯;(+)-Biotin 4-nitrophenyl ester
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years