Azido-PEG3-azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
Azido-PEG3-azide is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
101187-39-7
分子式
C8H16N6O3
分子量
244.25
别名
1,11-二叠氮基-3,6,9-三氧杂十一烷
储存和溶解度
DMSO:100 mg/mL (409.42 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years