Boc-11-aminoundecanoic acid 是一种属于 Alkyl/ether 类的 PROTAC linker,可用于 MS432 的合成。
产品描述
Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker that can be used in the synthesis of MS432.
体外活性
MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2[1]. PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Cas No.
10436-25-6
分子式
C16H31NO4
分子量
301.42
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years